| Cast/Characters | |
| Want to find out who played Mrs. Garrett on the show? Why she left the series? You can find a cast and character profile on each major actress/actor on the show. | |
| Actor/Actress | Character Name | Year On Series |
| Charlotte Rae | Edna Garrett | 1979-1985 |
| Lisa Whelchel | Blair Warner | 1979-1988 |
| Kim Fields | Dorothy Ramsey | 1979-1988 |
| Mindy Cohn | Natalie Green | 1979-1988 |